Razhali, Nur Farahalya (2023) Hemodynamic analysis on different stent strut configuration of femoral popliteal artery for physical and physiological condition. Masters thesis, Universiti Tun Hussein Onn Malaysia.

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Abstract

Peripheral arterial disease (PAD) is a narrowing of the peripheral arteries that might result in blockage if not immediately treated. Normally, an invasive technique called stenting is used at the stenosed arterial region to restore normal blood flow. However, it promotes the formation of thrombosis on the stented artery due to the presenting flow recirculation. However, the rate of thrombosis growth was reported to be different for both genders. This is due to an increase in body surface area, body mass index, and weight of the body. Furthermore, different vascular regions have presented different flow characteristics that highly depend on the vascular physical condition. Thus, this study aims to investigate the effect of the physiological and physical conditions of men and women with different hemodynamic parameters on the strut configuration in femoral popliteal artery. Five different stent strut configurations were modelled and inserted into the femoral popliteal artery. The computational fluid dynamic (CFD) method was implemented to solve the continuity and Nevier Stokes equations. The hemodynamic performance of the stent was analysed based on hemodynamic parameters consisting of time-averaged wall shear stress (TAWSS), time-averaged wall shear stress gradient (TAWSSG), oscillatory shear index (OSI), and relative residence time (RRT). According to the observations, the distal region of the stented femoral popliteal artery had more dominant flow re-circulation than the proximal region. The high void area contributed to less growth of the thrombosis. The pictorial selection method was used to evaluate the best hemodynamic stent performance based on a scoring system. In all cases, Type I stents showed the best hemodynamic parameter performance over the other stented femoral popliteal artery with an average score of 4.14, followed by Type III, Type V, Type II, and Type IV with an average score of 3.47, 3.10, 2.97, and 1.31, respectively

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